Molecular Search Machines

Like the Google search engine reacts on your requests, Molecular Search Machines (MSM) will experimentally provide you information about relevant molecules or molecule-based processes. Molecular Search Machines copy evolutionary principle: they use the diversity of the combinatorial molecules and the selection of binding events in the array format. Generation of high density molecular arrays is the main goal of our research. To develop the Molecular Search Machines, we use our ERC-grant awarded approach to combinatorial patterning of bioparticles. We also develop MSM-applications in life and material sciences.

1998
M.S. Degree with Honor in Physics from Lomonosov Moscow State University


2000
PhD Degree in Laser Physics from Institute of Laser&Information Technologies in Schatura


2006 
PhD degree in Biotechnology from University of Heidelberg/ German Cancer Research Center


2008 
Assistant Professor (Priv.-Doz.) at University of Heidelberg


2010 
Group Leader at Karlsruhe Institute of Technology, Institute of Microstructure Technology

Awards: ERC Starting Grant (2011), Helmholtz Association Price (2011), HRJRG-Grant (2011)

Loffler F., Cheng Y.-C., Fortsch T., Dorsam E., Bischoff R., Breitling F. and Nesterov-Müller A.  (2011) Biofunctional Xerography, InTech,  in  Biotechnology of Biopolymers ISBN 978-953-307-179-4, p 275-290

Breitling, F., Löffler, F., Schirwitz, C., Cheng, Y.C., Märkle, F., König, K., Felgenhauer, T., Dörsam, E., Bischoff, F.R., Nesterov-Müller, A. (2011) Alternative Setups for Automated Peptide Synthesis. Mini Reviews in Organic Chemistry. V8: 121-131

Nesterov-Müller, A., Dörsam, E., Cheng, Y.C., Schirwitz, C., Märkle, F., Löffler, F., König, K., Stadler, V., Bischoff, F.R. & Breitling, F. (2010) Peptide arrays with a chip. Methods Mol Biol. 669:109-24.

Nesterov-Müller A., König K., Felgenhauer T., Lindenstruth V., Trunk U., Fernandez S., Hausmann M., Bischoff F. R., Stadler V., Breitling F., Precise selective deposition of microparticles on electrodes of microelectronic chips, (2008) Review of Scientific Instruments 79, 035106

Beyer, M., Nesterov-Müller, A. (shared first author), Block, I., Konig, K., Felgenhauer, T., Fernandez, S., Leibe, K., Torralba, G., Hausmann, M., Trunk, U., Lindenstruth, V., Bischoff, F. R., Stadler, V., and Breitling F. (2007) Combinatorial synthesis of peptide arrays onto a microchip. Science 318, 1888-1888.

Niziev V.G., Nesterov-Müller A. Influence of Beam Polarization on Laser Cutting Efficiency. Journal of Physics D Appl. Phys. 1999; 32: 1455-1461.